Optimal Model Based Control for Blood Glucose Insulin System Using Continuous Glucose Monitoring

The level of glucose control in the human body is very important, because increase in glucose level in diabetic patients for long time causes blindness and cardiovascular problem. In this paper, closed loop insulin system for diabetic patients is proposed to regulate the blood glucose level. Hence, continuous monitoring and control of glucose level is necessary for Type 1 diabetes patients. In this paper, Bergeman minimal model is consider and then closed loop system is developed with insulin pump. This closed loop system essentially acts as an artificial pancreas. The closed loop control parameters are optimally tuned to control the blood glucose level most effectively. The Internal model control (IMC) and proportional derivative (PD) controller are implemented and the control parameters are tuned optimally. The comparative simulation results are compared and analysed.